- A calcium channel blocker primarily used for the rapid management of acute heart rhythm disorders
Uses
- Supraventricular Tachyarrhythmias:
- Used to rapidly convert paroxysmal supraventricular tachycardia (PSVT) to normal sinus rhythm
- Rate Control:
- Provides temporary control of fast ventricular rates in atrial flutter or atrial fibrillation
- Other Uses:
- Sometimes used for cluster headache prophylaxis or specific pediatric cases
Features
- Formulation & Administration:
- A sterile, 2.5 mg/mL solution, administered via slow IV injection (over 2+ minutes) under continuous ECG/BP monitoring
- Mechanism:
- Inhibits calcium ion influx, slowing AV conduction and prolonging the refractory period
- Rapid Onset:
- Peak effects occur within 3 to 5 minutes
- Packaging:
- 2mL single-dose vials, reducing contamination risk
Benefits
- High Success Rate:
- Converts ~60% of supraventricular tachycardia patients within 10 minutes
- Effective Rate Control:
- Reduces heart rate by 20%+ in ~70% of atrial flutter/fibrillation patients
- Cardiovascular Support:
- Improves coronary blood flow and lowers cardiac workload
- Pediatric Use:
- Used for children with appropriate weight-based dosing
